GLUCOSE-SOLOPHARM™ POLYFLAC DOMUS infusion solution 5% (200ml), vial 1pc

GLUCOSE-SOLOPHARM™ 5% Solution 200ml Buy Online

Glucose-Solopharm Polyflac Domus Infusion Solution 5%

Maintaining proper hydration and energy levels is crucial for overall health. Glucose-Solopharm Polyflac Domus Infusion Solution 5% provides a readily available source of energy and hydration, making it a valuable tool in various medical situations.

This isotonic solution is designed for intravenous administration and offers a simple way to replenish fluids and provide essential glucose.

Glucose is an essential nutrient, providing the body’s cells with energy. When oral intake is insufficient or impossible, intravenous glucose solutions become vital. Glucose-Solopharm Polyflac Domus Infusion Solution 5% offers a convenient and effective method for delivering this crucial energy source directly into the bloodstream. This isotonic solution is designed for intravenous administration, effectively addressing fluid and glucose deficiencies. Its simple composition and administration make it a valuable tool in various medical settings, from routine hydration to supporting patients recovering from illness or surgery. Understanding its properties, uses, and potential side effects is crucial for healthcare professionals and patients alike. This detailed overview will explore the key aspects of Glucose-Solopharm Polyflac Domus Infusion Solution 5%, providing a comprehensive understanding of its clinical applications and potential benefits.

The 5% concentration makes it suitable for a range of clinical situations where fluid and glucose replenishment are needed. This solution is particularly valuable in cases of dehydration due to various causes, including vomiting, diarrhea, or post-surgical recovery. Its isotonic nature minimizes the risk of significant fluid shifts, contributing to safer administration. Furthermore, its role as a vehicle for other medications enhances its versatility in the clinical setting.

This in-depth analysis will delve into the composition, pharmacological actions, indications, precautions, and potential side effects, offering a comprehensive understanding of its clinical utility and safety profile. We will also examine the appropriate administration methods and dosage guidelines to ensure safe and effective use. The information provided aims to equip healthcare professionals with the knowledge necessary to utilize this solution appropriately and effectively manage potential risks.

Composition and Properties

Glucose-Solopharm Polyflac Domus Infusion Solution 5% is primarily composed of dextrose monohydrate, a form of glucose, as its active ingredient. This provides a readily available source of energy for cellular metabolism. The solution also contains small amounts of sodium chloride to help maintain electrolyte balance and adjust tonicity. Finally, water for injection serves as the solvent, ensuring the solution is suitable for intravenous administration.

The solution’s isotonic nature is a crucial property. This means its osmotic pressure is similar to that of blood plasma, minimizing the risk of fluid shifts that could harm the patient. The 5% concentration of dextrose provides a moderate source of energy without causing rapid hyperglycemia in most individuals. This balance of energy provision and osmotic compatibility makes it suitable for a wide range of clinical situations where fluid and energy replacement is needed. The solution is packaged in a convenient, single-use vial, ensuring sterility and ease of administration. This packaging also contributes to its overall stability and shelf life.

The sterility of the solution is paramount for safe intravenous use. Rigorous manufacturing processes ensure the absence of pyrogens and other contaminants that could cause adverse reactions. The solution’s clarity and absence of particulate matter are visual indicators of its quality and suitability for administration. Its physical properties, including viscosity and osmolarity, are carefully controlled during manufacturing to ensure optimal intravenous delivery and patient safety. These carefully controlled properties contribute to the solution’s effectiveness and safety in clinical settings.

Pharmacological Action

The primary pharmacological action of Glucose-Solopharm Polyflac Domus Infusion Solution 5% centers on its role as a readily available source of energy for cellular metabolism. Once administered intravenously, the dextrose is rapidly absorbed into the bloodstream and transported to various tissues throughout the body. Inside cells, dextrose undergoes phosphorylation, transforming into glucose-6-phosphate, a key intermediate in numerous metabolic pathways. This process fuels essential cellular functions and supports overall bodily functions.

Beyond its role as an energy source, the infusion contributes to fluid balance. In cases of dehydration, the isotonic nature of the solution ensures that fluid is distributed effectively throughout the body without causing significant osmotic shifts. This replenishment of fluids is particularly important in situations of significant fluid loss, such as vomiting, diarrhea, or post-surgical recovery. The gentle rehydration prevents dehydration-related complications, supporting overall patient recovery.

Furthermore, the solution can serve as a vehicle for other medications. Its compatibility with various drugs allows for the simultaneous administration of other necessary treatments, simplifying the infusion process. This combined administration simplifies treatment regimens and minimizes the need for multiple intravenous lines, increasing overall patient convenience. The solution’s ability to support other treatments enhances its versatility and effectiveness in a range of clinical scenarios. The solution’s role in delivering other drugs requires careful consideration of compatibility to prevent adverse reactions.

Uses and Indications

Glucose-Solopharm Polyflac Domus Infusion Solution 5% finds application in various clinical scenarios where fluid and energy replenishment are necessary. Its primary use is rehydration in cases of fluid loss due to conditions such as vomiting, diarrhea, or excessive sweating. The isotonic nature of the solution makes it ideal for restoring fluid balance without causing significant electrolyte imbalances. This gentle rehydration is crucial for supporting overall patient well-being and recovery.

The solution also serves as a valuable source of energy, particularly when oral intake is limited or impossible. The readily available glucose provides the body’s cells with the fuel needed for essential metabolic processes. This energy support is beneficial for patients recovering from surgery, illness, or trauma, helping to accelerate their recovery. The solution can be particularly useful for patients with increased energy demands, such as those with burns or infections.

Furthermore, Glucose-Solopharm Polyflac Domus Infusion Solution 5% acts as a vehicle for other medications, enhancing its clinical versatility. Its compatibility allows for the simultaneous administration of various drugs, simplifying the infusion process and reducing the need for multiple intravenous lines. This feature proves particularly useful in situations requiring combined therapies, such as post-operative pain management or antibiotic administration. This combined approach streamlines care and minimizes the burden on patients undergoing multiple treatments.

Pros

Glucose-Solopharm Polyflac Domus Infusion Solution 5% offers several key advantages in clinical settings. Its isotonic nature minimizes the risk of fluid shifts and electrolyte imbalances, making it a safe and effective rehydration solution. This is especially valuable for patients who are already vulnerable due to illness or other medical conditions. The solution’s gentle action makes it suitable for a broad range of patients.

The solution’s readily available glucose provides a convenient and efficient source of energy for cellular metabolism, particularly crucial when oral intake is compromised. This energy support is essential for patients recovering from surgery, illness, or trauma, aiding in their recovery. The direct intravenous delivery ensures rapid absorption and utilization of the glucose, bypassing the digestive system.

Furthermore, its use as a vehicle for other medications simplifies treatment regimens. The ability to administer multiple drugs simultaneously reduces the need for multiple intravenous lines, increasing patient comfort and decreasing the risk of infection at multiple injection sites. This streamlined approach improves the efficiency of care while minimizing patient discomfort. Its compatibility with a wide range of medications makes it a versatile tool in the clinical setting.

Finally, the single-use vial packaging ensures sterility and ease of administration, reducing the risk of contamination and making the solution convenient to use. This practical design minimizes preparation time for healthcare professionals and contributes to a more efficient workflow. The ready-to-use format contributes to improved patient safety and reduces the potential for errors during preparation.

Cons

While generally safe and effective, Glucose-Solopharm Polyflac Domus Infusion Solution 5% has some potential drawbacks. The primary concern is the risk of hyperglycemia, particularly in patients with pre-existing diabetes or impaired glucose tolerance. Careful monitoring of blood glucose levels is essential, especially during prolonged infusions or in vulnerable patient populations. Adjusting the infusion rate or administering insulin may be necessary to manage blood sugar levels.

Another potential issue is the risk of fluid overload, especially in patients with cardiac or renal impairment. Close monitoring of fluid balance, including intake and output, is crucial to prevent complications. Overhydration can strain the circulatory system and lead to edema, particularly in patients with compromised cardiac or renal function. Careful attention to fluid balance is therefore crucial during administration.

Furthermore, the solution’s use as a vehicle for other medications necessitates careful consideration of drug compatibility. Mixing incompatible drugs could result in precipitation or degradation of the active ingredients, potentially compromising the effectiveness or safety of the treatment. Healthcare professionals must rigorously check for compatibility before mixing medications with the solution. Incorrect mixing may lead to adverse effects or treatment failure.

Finally, although rare, local reactions at the infusion site, such as phlebitis or inflammation, are possible. Proper aseptic techniques during administration are crucial to minimize this risk. Selecting appropriate intravenous sites and closely monitoring the insertion site for signs of inflammation are essential for minimizing complications. Early detection and management of local reactions are critical for preventing more severe issues.

Precautions and Contraindications

Before administering Glucose-Solopharm Polyflac Domus Infusion Solution 5%, healthcare professionals must carefully consider several precautions and contraindications. Patients with decompensated diabetes mellitus should receive this solution with extreme caution due to the risk of hyperglycemia. Close monitoring of blood glucose levels is essential, and insulin administration may be required to manage blood sugar levels effectively. The risk of hyperglycemic complications necessitates careful consideration in diabetic patients.

Patients with known glucose intolerance, including those experiencing metabolic stress, should also be closely monitored. The risk of hyperglycemia is heightened in these individuals, requiring careful adjustment of the infusion rate and close observation for any signs of hyperglycemic complications. Pre-existing conditions affecting glucose metabolism necessitate careful consideration and close monitoring during administration.

Furthermore, individuals with hyperosmolar coma or those exhibiting hyperglycemia and hyperlactacidemia should not receive this solution. These conditions represent contraindications due to the potential for worsening existing imbalances. The solution is inappropriate for patients with severe metabolic disturbances that could be exacerbated by the administration of additional glucose. Contraindications should always be carefully considered before initiating treatment.

Additional precautions include avoiding administration within the first 24 hours following head trauma and carefully assessing for any allergies or sensitivities to the solution’s components. These precautions aim to minimize potential risks and ensure patient safety. A thorough assessment of the patient’s medical history is crucial before administering the solution.

Administration and Dosage

Glucose-Solopharm Polyflac Domus Infusion Solution 5% is administered intravenously via a drip infusion. The specific dosage and infusion rate are determined by the patient’s individual needs and clinical condition, always under the guidance of a healthcare professional. Factors such as the severity of dehydration, the patient’s overall health status, and the presence of any underlying conditions influence dosage determination. Dosage should always be tailored to the specific needs of the patient.

The infusion rate should be carefully controlled to prevent rapid changes in blood glucose levels. Slow and steady administration is generally recommended to minimize the risk of hyperglycemia and other adverse effects. Monitoring blood glucose levels throughout the infusion process allows for timely adjustments in the infusion rate. Close observation helps prevent potential complications.

For adult patients, the maximum infusion rate is typically set at a level that prevents rapid changes in blood sugar. This rate is determined considering individual patient factors and clinical judgement. The total daily dosage should be carefully calculated based on the patient’s specific requirements. The overall fluid volume administered must also be considered, particularly in patients with cardiac or renal impairment.

In pediatric patients and those with impaired renal or cardiac function, the dosage and infusion rate should be adjusted according to the patient’s specific needs. These adjustments are crucial for preventing fluid overload and minimizing the risk of adverse effects. Specialized dosing guidelines may be necessary for specific patient populations. Always consult with a healthcare professional for accurate dosage and administration guidelines.

Monitoring and Side Effects

Close monitoring of the patient is crucial during and after the administration of Glucose-Solopharm Polyflac Domus Infusion Solution 5%. Regular assessment of vital signs, including heart rate, blood pressure, and respiratory rate, is necessary to detect any adverse reactions. Continuous monitoring of fluid balance, including intake and output, helps prevent fluid overload and electrolyte imbalances. These parameters provide critical information about the patient’s response to the infusion.

Blood glucose levels should be monitored regularly, especially in patients with diabetes or impaired glucose metabolism. Frequent blood glucose checks allow for early detection of hyperglycemia, enabling prompt adjustments to the infusion rate or insulin administration. This proactive approach minimizes the risk of serious hyperglycemic complications. The frequency of monitoring depends on the patient’s individual risk factors and clinical status.

Potential side effects, though generally mild, include hyperglycemia, glucosuria, and hyperosmolar hyperglycemic state. These are more likely in patients with pre-existing conditions affecting glucose metabolism. Less common side effects can involve fluid imbalances, such as hypervolemia, and local reactions at the infusion site, such as phlebitis or thrombophlebitis. Appropriate measures should be taken to address these side effects as they arise.

In the event of any adverse reaction, the infusion should be stopped immediately, and appropriate supportive measures should be implemented. Healthcare professionals should be prepared to manage potential complications, such as hyperglycemia or fluid overload. Prompt intervention is essential for minimizing the severity of adverse events. Careful monitoring and prompt intervention are crucial for ensuring patient safety and well-being.